PT-141 32780-32-8 Injectable Peptides ,Pharmaceutical Peptide Bremelanotide

Pharmaceutical Peptide Bremelanotide PT-141 

Quick Details
 

 
 
Description
PT-141 (Bremelanotide) is a highly potent synthetic peptide analogue of α-MSH that may elicit aphrodisiac effects through stimulation of melanocortin receptors. PT-141 (Bremelanotide) consists of seven amino acids and is a cyclic, shortened lactam variant of alpha-Melanocyte-stimulating hormone (α-MSH), a multifunctional peptide that regulates a broad array of physiological functions. In studies, bremelanotide was shown to induce lordosis in an animal model and was also effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).
 
Specification
Name: PT-141
Synonyms: Bremelanotide, PT-141 Acetate
CAS #: 189691-06-3
Molecular Formula: C50H68N14O10
Molecular Mass: 1025.2 Da (g/mol)
Amino Acid Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
 

 
Purity
PT-141 has a peptide purity level that exceeds 99.0% as determined by HPLC and MS. This peptide was synthesized with no additives and is supplied as a white lyophilized (freeze-dried) powder.
 
Usage
Bremelanotide, similarly to its analogues α-MSH and melanotan II, acts as a non-selective agonist of all of the melanocortin receptors except MC2, where it lacks significant affinity. Reported activity of the drug is as follows:
MC1 (Ki = 0.68 nM)
MC2 (Ki > 1000 nM)
MC3 (Ki = 72.07 nM)
MC4 (Ki = 19.25 nM)
MC5 (Ki = 166.8 nM)
Bremelanotide appears to stimulate sexual desire and arousal completely or mostly via activation of the MC4 receptor (the MC3 receptor may also be involved). It modulates inflammation and limits ischemia via activation of the MC1 and MC4 receptors.
According to Palatin Technologies' original 2003 patent for bremelanotide, it possesses approximately 50 times the potency of melanotan II as an inducer of erection in male rats. In addition, it was stated in the patent that the therapeutic window of bremelanotide in animals (specifically, the range of induction of the desired sexual arousal relative to the induction of side effects including nausea, yawning, stretching, and decreased appetite) was >1,000-fold, whereas that of melanotan II was only 3- to 4-fold. They concluded that bremelanotide would be more tolerable than melanotan II.
 

 
Our Lab supply four service:
1. Petides:Peptides are all from Labs.We could synthesis in lab whatever you need.
2. Steriods Raw Powder:Our boss have Steriods Raw Powder Facotry in his hometown With 99% Purity only.No cheaper stuff available here.
3. Steriods Oil and Tablets:we have but only sell in Bulk Order or sell together with our Peptides.Not sell seperately. (Mostly are for our Regular Clients only.For Chinese Policies.)
4. Custom-Made Service:If you need our Factory make your own Brands for you, we have Quantity Requirements per time.

VIP Clients Policy:
If your Purchasing Total Amount in our company per year could reach 50,000 USD,at the end of year ,we could use 2%-5% of the Total Amount to send Free goods.

Customer Types which had more support:
1.Potential customer
(With Purchasing Data +Clients'Current Market Clients Number and Products Quantity per month to apply)

2.Stable customer group and stable Quantity Order per month
(With complete Purchasing Data with our company to Apply)

3.Regular Personal Users
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4.Clients who have funds and have plan to expand market
(With Purchasing Data +Clients'Current Market Clients Number and Products Quantity per month to apply)
**Current Real Data+Future Market(Based on Current)