|No.8 Jinshun Road Zhuqiao Pudong New District,Shanghai,Chinafirstname.lastname@example.org|
|Place of Origin:||China|
|Minimum Order Quantity:||10 vials|
|Packaging Details:||10iu/vial, 36iu/vial or as required|
|Delivery Time:||Within 7 working days|
|Payment Terms:||L/C, T/T, , MoneyGram,Alipay|
|LimitNum:||10 Vials||DeliveryTime:||Within 7 Working Days|
|Purity:||99%||Storage:||Dry, Dark And Ventilated Place|
peptides for muscle growth,
injectable human growth hormone
Pharmaceutical Peptide Bremelanotide 32780-32-8 PT-141
|CAS No.:||32780-32-8||Other Names:||PT 141||MF:||C7H15NO4|
|EINECS No.:||258279-04-8||Place of Origin:||ShangHai, China (Mainland)||Type:||Auxiliaries and Other Medicinal Chemicals|
|Grade Standard:||Medicine Grade||Usage:||Animal Pharmaceuticals, Bodybuilding|
|Model Number:||Purity:||99%min||Product Name:||PT141|
|Colour:||White||Export Markets:||Global||Production Capacity:||10000g|
PT-141 (Bremelanotide) is a highly potent synthetic peptide analogue of α-MSH that may elicit aphrodisiac effects through stimulation of melanocortin receptors. PT-141 (Bremelanotide) consists of seven amino acids and is a cyclic, shortened lactam variant of alpha-Melanocyte-stimulating hormone (α-MSH), a multifunctional peptide that regulates a broad array of physiological functions. In studies, bremelanotide was shown to induce lordosis in an animal model and was also effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).
Synonyms: Bremelanotide, PT-141 Acetate
CAS #: 189691-06-3
Molecular Formula: C50H68N14O10
Molecular Mass: 1025.2 Da (g/mol)
Amino Acid Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
PT-141 has a peptide purity level that exceeds 99.0% as determined by HPLC and MS. This peptide was synthesized with no additives and is supplied as a white lyophilized (freeze-dried) powder.
Bremelanotide, similarly to its analogues α-MSH and melanotan II, acts as a non-selective agonist of all of the melanocortin receptors except MC2, where it lacks significant affinity. Reported activity of the drug is as follows:
MC1 (Ki = 0.68 nM)
MC2 (Ki > 1000 nM)
MC3 (Ki = 72.07 nM)
MC4 (Ki = 19.25 nM)
MC5 (Ki = 166.8 nM)
Bremelanotide appears to stimulate sexual desire and arousal completely or mostly via activation of the MC4 receptor (the MC3 receptor may also be involved). It modulates inflammation and limits ischemia via activation of the MC1 and MC4 receptors.
According to Palatin Technologies' original 2003 patent for bremelanotide, it possesses approximately 50 times the potency of melanotan II as an inducer of erection in male rats. In addition, it was stated in the patent that the therapeutic window of bremelanotide in animals (specifically, the range of induction of the desired sexual arousal relative to the induction of side effects including nausea, yawning, stretching, and decreased appetite) was >1,000-fold, whereas that of melanotan II was only 3- to 4-fold. They concluded that bremelanotide would be more tolerable than melanotan II.
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Efficacy of each phase:
1. The first month: sleep improvement, add strength, reduce physical fatigue, looking shiny, rosy, reduce hair loss, vision (presbyopia) improved, abdominal fat reduction. Reduce women's sense of dryness,male reproductive improvement significantly. Enhance sexual desire, enhance physical power.
2. Second months: memory significantly enhanced immune ability, skin pigmentation, facial deep wrinkles become shallow, small wrinkles disappear.
3. The third month: to further enhance the above results, improve the speed to achieve balance, the depth of the repair process in progress;
4. The fourth month: the skin shiny, moist, delicate, elastic wrinkles further subsided, abdominal circumference decreased, there is a better sports endurance, the spirit is in an optimistic state;
5. Fifth, sixth months:to restore the state of the skin to young age, body contour to better, the body function to be improved in all directions.
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