|No.8 Jinshun Road Zhuqiao Pudong New District,Shanghai,Chinafirstname.lastname@example.org|
|Place of Origin:||China|
|Minimum Order Quantity:||10vials|
|Packaging Details:||Plastic ,bubble, silver paper, 1kg/bag, 100g/bag|
|Delivery Time:||1-2 works day|
|Payment Terms:||T/T, , MoneyGram|
|Supply Ability:||10000vial / month|
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Pharmaceutical Peptide Bremelanotide 32780-32-8 PT-141
|CAS No.:||32780-32-8||Other Names:||PT 141||MF:||C7H15NO4|
|EINECS No.:||258279-04-8||Place of Origin:||ShangHai, China (Mainland)||Type:||Auxiliaries and Other Medicinal Chemicals|
|Grade Standard:||Medicine Grade||Usage:||Animal Pharmaceuticals, Bodybuilding|
|Model Number:||Purity:||99%min||Product Name:||PT141|
|Colour:||White||Export Markets:||Global||Production Capacity:||10000g|
PT-141 (Bremelanotide) is a highly potent synthetic peptide analogue of α-MSH that may elicit aphrodisiac effects through stimulation of melanocortin receptors. PT-141 (Bremelanotide) consists of seven amino acids and is a cyclic, shortened lactam variant of alpha-Melanocyte-stimulating hormone (α-MSH), a multifunctional peptide that regulates a broad array of physiological functions. In studies, bremelanotide was shown to induce lordosis in an animal model and was also effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).
Synonyms: Bremelanotide, PT-141 Acetate
CAS #: 189691-06-3
Molecular Formula: C50H68N14O10
Molecular Mass: 1025.2 Da (g/mol)
Amino Acid Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
PT-141 has a peptide purity level that exceeds 99.0% as determined by HPLC and MS. This peptide was synthesized with no additives and is supplied as a white lyophilized (freeze-dried) powder.
Bremelanotide, similarly to its analogues α-MSH and melanotan II, acts as a non-selective agonist of all of the melanocortin receptors except MC2, where it lacks significant affinity. Reported activity of the drug is as follows:
MC1 (Ki = 0.68 nM)
MC2 (Ki > 1000 nM)
MC3 (Ki = 72.07 nM)
MC4 (Ki = 19.25 nM)
MC5 (Ki = 166.8 nM)
Bremelanotide appears to stimulate sexual desire and arousal completely or mostly via activation of the MC4 receptor (the MC3 receptor may also be involved). It modulates inflammation and limits ischemia via activation of the MC1 and MC4 receptors.
According to Palatin Technologies' original 2003 patent for bremelanotide, it possesses approximately 50 times the potency of melanotan II as an inducer of erection in male rats. In addition, it was stated in the patent that the therapeutic window of bremelanotide in animals (specifically, the range of induction of the desired sexual arousal relative to the induction of side effects including nausea, yawning, stretching, and decreased appetite) was >1,000-fold, whereas that of melanotan II was only 3- to 4-fold. They concluded that bremelanotide would be more tolerable than melanotan II.
-----------Additional Information ------------
Place of origin:China
-----------Delivery Information -------------
Packing : Plastic Tube/vials or as your request
Payment : T/T,
Port : Shanghai, Shenzhen,Gunagzhou Hongkong
Shipment method : EMS,TNT, DHL, FeDex, UPS, etc
Leading time : Within 24 hours after payment
Delivery time : safe & timely, around 3 days after payment.
----------Our Competitive Advantages -----------
1. Rich experience.
Our company is a professional production leading factory in China in pharmaceutical area of many years
2. Superior quality, purity and favourable.
Our company is a professional leading manufacturer in China in pharmaceutical area.Good quality is one of our secret success.
3. Safe and fast delivery.
We have GOLDEN FORWARDER and UK Warehouse so we can delivery quickly and safely.
4. Package: Professional packing with professional materials.
5. Competitive Prices : Low price with high qulity.
Q1: How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC ,
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
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we'd like to accept T/T , Moneygram , .
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For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
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we have good after-sale service and re-shipment policy if the parcel lose
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our clients will confirm this as even they struggle to find them without help at times.
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